Construction Process of SGS Class 100,000 Sterile Room Project
I. Introduction
In many industries with high requirements for microbial control, such as pharmaceuticals, medical devices, and food processing, the SGS Class 100,000 sterile room plays a crucial role. As a professional manufacturer of purification equipment, Guangzhou Cleanroom Construction Co., Ltd. has extensive experience in the construction of sterile rooms. Today, we will provide you with a detailed analysis of the construction process of the SGS Class 100,000 sterile room project, helping you gain an in - depth understanding of the intricacies behind this precise project.
II. Pre - project Preparation Stage
A. Requirement Communication and Assessment
Communicate closely with clients to understand the characteristics of their industries, production process requirements, and specific functional expectations for the sterile room. For example, pharmaceutical companies may need to focus on the control of drug dust and the adaptation of aseptic operation processes; food processing companies may focus on preventing the impact of microbial growth on product shelf - life.
Conduct on - site inspections of the construction site to evaluate its basic conditions, including the stability of the building structure, ventilation and lighting conditions, and the available space size. This step provides key basis for the subsequent design of the plan, ensuring that the sterile room can be perfectly integrated into the site environment.
B. Scheme Design and Planning
Based on the previous communication and inspection results, the company's professional design team carefully draws the construction blueprint of the SGS Class 100,000 sterile room. In terms of layout, reasonably divide functional areas, such as the purification operation area, material storage area, and personnel passageways, to ensure that the flow of people, materials, and air does not interfere with each other.
Carefully plan the purification system, including the precise positioning of air supply outlets, air return outlets, and exhaust outlets, the selection of air filters (a combination of primary, medium - efficiency, and high - efficiency filters to meet the Class 100,000 purification standard), and the accurate calculation of fresh air volume and air change rate to ensure that the indoor air continuously meets the aseptic requirements.
C. Material and Equipment Selection and Procurement
Strictly select building materials that meet the quality standards of the SGS Class 100,000 sterile room according to the design plan. For walls, choose color - coated steel plates with excellent air - tightness, smooth surface, and easy - to - clean properties; for the floor, use anti - static, corrosion - resistant, and seamless epoxy self - leveling materials.
Carefully select purification equipment. From fans, air - conditioning units to air purification devices, all choose well - known brands in the industry with excellent performance and products that have passed strict tests to ensure the stable operation of the equipment and lay the foundation for the long - term and efficient operation of the sterile room.
III. On - site Construction Stage
A. Basic Engineering Construction
First, carry out ground treatment. Grind and clean the original ground to ensure that there is no dust or oil residue. Subsequently, lay the anti - static epoxy self - leveling floor, strictly controlling the flatness error within a very small range to ensure the stable installation of subsequent equipment.
Build the wall framework according to the design requirements. Use high - quality aluminum alloy or light - steel keels to ensure the structural strength. When installing the color - coated steel plate walls, pay attention to the tightness of the plate joints and seal them with professional sealants to prevent air leakage.
B. Installation of Purification System
Install the air supply and exhaust ducts. The duct materials are selected from high - quality galvanized steel plates or stainless - steel plates with a smooth inner wall to reduce air resistance and the risk of dust accumulation. Connect the ducts in strict accordance with the specifications to ensure airtightness. During the installation process, conduct light - leakage detection at any time to discover and correct problems in a timely manner.
Install the primary, medium - efficiency, and high - efficiency air filters in sequence. Check the integrity of the filters before installation. Handle them with care during installation to avoid damage, ensuring that the gaskets fit tightly and the filtration efficiency meets the standards. Install the fans and air - conditioning units simultaneously, adjust the fan speed and air pressure, and calibrate the temperature and humidity control parameters of the air - conditioner to make the purification system operate in coordination.
C. Installation of Electrical and Lighting Systems
Lay cables and wires according to the electrical design drawings. Adopt the concealed wiring method through pipes. The pipe materials are selected from fire - resistant and corrosion - resistant PVC pipes or galvanized steel pipes to prevent safety hazards caused by exposed wires.
Install lighting fixtures. Select glare - free and evenly illuminated clean fluorescent lamps or LED lamps to meet the lighting needs of different areas in the sterile room. The installation of the lamps is well - sealed and easy to clean. At the same time, equip an emergency lighting system to ensure the safe evacuation of personnel in case of a sudden power outage.
D. Detail Optimization and Improvement
Install doors and windows carefully. Select air - tight doors, install door closers and access control systems to ensure smooth opening and closing and strong airtightness. Use double - layer insulating glass for windows, which not only meets the lighting requirements but also blocks external pollution.
Install water supply and drainage pipes. Select stainless - steel pipes that meet the hygienic standards as the pipe materials. Set up reasonable water seals and traps to prevent the back - flow of odors and microorganisms, ensuring the safety and hygiene of water use and drainage.
IV. Commissioning and Testing Stage
A. Purification System Commissioning
Start the purification system and gradually adjust parameters such as fan speed, fresh air volume, and return air ratio. Observe the indoor air flow pattern. Use methods such as smoke testing to visually check whether the air flow is uniform and free of turbulence, ensuring that the air circulation mode meets the requirements of the Class 100,000 purification standard.
Commission the air - conditioning unit. Accurately calibrate the temperature and humidity sensors to keep the indoor temperature and humidity stable within the specified range, such as a temperature of 18 - 26°C and a humidity of 45% - 65%, creating a comfortable environment for aseptic operation.
B. Testing and Acceptance
Entrust a professional third - party testing agency to comprehensively test the sterile room according to the SGS standards and relevant national standards. This includes air cleanliness testing, using a dust particle counter to measure the concentration of particulate matter of different particle sizes; and microbial testing, analyzing and evaluating the degree of microbial contamination through the sampling of sedimentation bacteria and planktonic bacteria.
Test items such as electrical safety, lighting illuminance, and grounding resistance to ensure that all indicators meet the specifications. Only when all test items are qualified can the sterile room be officially delivered for use.
V. Post - project Maintenance Stage
A. Regular Equipment Maintenance
Develop a detailed maintenance plan for purification equipment. Regularly maintain equipment such as fans, air - conditioning units, and air filters. For example, check the wear of fan bearings every quarter and replace the high - efficiency air filters every year to ensure the continuous stable performance of the equipment.
Establish an emergency response mechanism for equipment failures. Equip professional maintenance personnel who can respond quickly in case of sudden equipment failures and restore the operation of the sterile room in the shortest possible time to reduce production losses.
B. Environmental Monitoring and Continuous Optimization
Continuously monitor the air quality of the sterile room. Regularly sample and test the number of dust particles and the content of microorganisms. According to the monitoring results, adjust the parameters of the purification system or take cleaning and disinfection measures in a timely manner to keep the indoor environment in line with the Class 100,000 aseptic standard at all times.
Collect user feedback, optimize and upgrade the layout and functions of the sterile room, and continuously improve the user experience to meet the development needs of the industry.
VI. Conclusion
The construction of the SGS Class 100,000 sterile room project is a rigorous and meticulous task. Every link is related to the quality and efficiency of the final sterile room. With professional technology, high - quality materials, and a rigorous process, Guangzhou Cleanroom Construction Co., Ltd. is committed to creating high - quality sterile rooms for customers, helping various industries to move towards higher production standards. If you have relevant needs, please feel free to contact us to start the journey of sterile room construction.
Construction Standards for Medicinal Excipient Cleanrooms
I. Introduction
In the pharmaceutical industry, the quality of medicinal excipients is of utmost importance for the safety and effectiveness of drugs. The environmental control during the production of medicinal excipients, especially the construction of cleanrooms, is a crucial aspect in ensuring product quality. Guangzhou Cleanroom Construction Co., Ltd., as a professional manufacturer of purification equipment, deeply understands the significance of the construction standards for medicinal excipient cleanrooms. The following will elaborate on these standards in detail.
II. Site - selection Requirements for Medicinal Excipient Cleanrooms
A. Environmental Factors
The cleanroom should be located far away from pollution sources, such as landfills and chemical plants. Atmospheric pollutants and microorganisms in the surrounding environment pose a potential threat to the production environment within the cleanroom. For example, in an industrial area, if there are many factories emitting exhaust gas nearby, it may increase the suspended particles in the air, thus affecting the purity of medicinal excipients.
It should be chosen in an area with good air quality and abundant greenery. Greenery can play a role in reducing dust and purifying the air, helping to create a relatively clean external environment for the cleanroom.
B. Geology and Terrain
The geological conditions of the selected site should be stable, avoiding earthquake - prone areas or regions prone to ground subsidence. Unstable geological conditions may cause cracks in the building structure of the cleanroom, damage its airtightness, and affect the purification effect.
The terrain should be flat, which is convenient for building construction and the installation and maintenance of purification equipment. If the terrain is undulating, it may bring difficulties to the design of the drainage system and air circulation system of the cleanroom.
III. Building Structure Standards for Cleanrooms
A. Walls and Floors
The walls should be made of materials with good air - tightness, such as color - coated steel plates. Color - coated steel plates have a smooth surface, are not prone to dust accumulation, and have good sealing performance, which can prevent external pollutants from entering the cleanroom.
The floor should be made of wear - resistant, corrosion - resistant, anti - static, and flat materials, such as epoxy self - leveling floors. The anti - static property can prevent static electricity from attracting dust and damaging production equipment, and the flat floor is convenient for cleaning and maintenance.
B. Doors and Windows
The doors and windows should be products with excellent air - tightness. The door usually adopts an air - tight door, which can fit tightly to the door frame when closed to prevent air leakage. If there are windows, double - or multi - layer insulating glass should be used, which can not only ensure lighting but also prevent heat transfer and the entry of pollutants.
The opening direction of the doors and windows should avoid disturbing the air flow organization in the cleanroom. For example, the door should open towards the side with higher pressure to ensure that a large amount of external polluted air is not introduced into the cleanroom when the door is opened.
IV. Air Purification System Standards for Cleanrooms
A. Air Supply and Exhaust
The cleanroom should be designed with a reasonable air supply and exhaust system according to the production process and cleanliness requirements. The air supply volume should ensure that the indoor air can be completely replaced within a specified time, generally calculated according to the cleanliness level and room volume. For example, for a medicinal excipient pulverization room with high cleanliness requirements, the air supply volume needs to meet a ventilation rate of more than [X] times per hour.
The exhaust system should be able to promptly discharge dust, odors, and harmful gases generated during the production process. For areas where volatile organic solvents are used, the exhaust system should also have explosion - proof functions.
B. Air Filtration
Air filtration is the core part of the air purification in the cleanroom. Generally, a combination of primary, medium - efficiency, and high - efficiency filters is used. The primary filter mainly filters large - particle dust, the medium - efficiency filter further filters medium - sized pollutants, and the high - efficiency filter is responsible for removing fine particles and microorganisms.
The selection of high - efficiency filters should be determined according to the cleanliness level of the cleanroom. For cleanrooms producing sterile medicinal excipients, H13 or H14 - grade high - efficiency filters are usually required, and their filtration efficiency for particles with a particle size of 0.3μm can reach 99.95% - 99.995%.
V. Temperature, Humidity, and Pressure Control Standards for Cleanrooms
A. Temperature and Humidity
The temperature in the medicinal excipient cleanroom is generally controlled between 18 - 26°C. Excessively high temperatures may cause some excipients to deteriorate. For example, some temperature - sensitive gel - like excipients may lose their original physical and chemical properties at high temperatures.
The humidity is usually controlled between 45% - 65%. Excessively high humidity is prone to the growth of microorganisms, while excessively low humidity may generate static electricity, affecting production operations and the quality of excipients.
B. Pressure
The cleanroom should maintain a certain positive pressure to prevent the intrusion of external polluted air. The pressure difference between rooms with different cleanliness levels is generally 5 - 10Pa. For example, between the excipient batching room (with a higher cleanliness level) and the corridor (with a lower cleanliness level), the pressure in the batching room should be higher than that in the corridor to ensure that the air in the corridor does not flow into the batching room.
VI. Lighting and Electrical Standards for Cleanrooms
A. Lighting
The lighting in the cleanroom should be uniform, bright, and glare - free. Generally, clean fluorescent lamps or LED lamps are used, and the illuminance should meet the needs of production operations. For fine - operation areas, such as the inspection platform for medicinal excipients, the illuminance should reach 300 - 500 lux to ensure that inspectors can accurately observe the appearance and quality of excipients.
The lamps should be of a sealed design to prevent dust from entering the lamp interior and to facilitate cleaning and maintenance.
B. Electrical
The electrical equipment in the cleanroom should have explosion - proof, dust - proof, and anti - static functions. All wires and cables should be laid in a concealed manner through pipes to avoid being exposed to the air, preventing dust accumulation and damage.
An emergency lighting system should be installed to ensure the safe evacuation of personnel and the emergency operation of important equipment in case of a sudden power outage. The emergency lighting time is generally not less than 30 minutes.
VII. Water Supply, Drainage, and Sanitary Facility Standards for Cleanrooms
A. Water Supply and Drainage
The water supply and drainage pipes in the cleanroom should be made of high - quality stainless steel or plastic pipes to prevent corrosion and leakage. The water supply pipes should be equipped with a filtering device to prevent impurities in the water from entering the cleanroom.
The drainage system should be designed with a reasonable water seal and trap to prevent odors and microorganisms from entering the cleanroom through the drainage pipes. For drainage with cleanliness requirements, such as equipment cleaning drainage, it should be treated to meet the corresponding water quality standards before being discharged.
B. Sanitary Facilities
If there are personnel operations in the cleanroom, sanitary facilities such as changing rooms, washbasins, and toilets that meet hygienic standards should be set up. The changing room should be divided into clean and non - clean areas. Before entering the cleanroom, personnel should change into clean work clothes in the changing room, and perform operations such as hand - washing and disinfection to prevent external pollutants from being brought into the cleanroom.
VIII. Conclusion
The construction of medicinal excipient cleanrooms is a systematic project that requires comprehensive consideration of various factors. With years of industry experience and professional technology, Guangzhou Cleanroom Construction Co., Ltd. can provide medicinal excipient manufacturers with high - standard cleanroom construction solutions and purification equipment, ensuring the cleanliness and safety of the production environment for medicinal excipients and safeguarding the quality of drugs.
Guangzhou Cleanroom Construction Co., Ltd.: Laboratory File Cabinets, Your Exclusive Data Stewards
In the daily operation of a laboratory, the proper management of various documents and materials is of utmost importance. As the professional Guangzhou Cleanroom Construction Co., Ltd., dedicated to creating high - quality purification equipment for laboratories, what we would like to introduce to you today is our meticulously developed laboratory file cabinets, which will become the solid guardians of your laboratory data.
I. Exceptional Materials for Durability
We are well - aware that the laboratory environment is complex and changeable, imposing high requirements on the durability of file cabinets. Therefore, the file cabinets produced by Guangzhou Cleanroom Construction Co., Ltd. are made of high - quality cold - rolled steel plates as the main material. These steel plates are finely processed, endowing the cabinets with excellent compressive and anti - deformation capabilities. Whether it is heavy experimental reports, research literatures, or long - term archived materials, the file cabinets can bear them steadily without issues such as skewed cabinet doors or sunken cabinets, ensuring long - term stability in use and providing a reliable storage place for your data.
II. Precise Design for Dust and Moisture Protection
Dust and moisture in the laboratory can easily damage precious materials if they penetrate the file cabinets. The file cabinets of Guangzhou Cleanroom Construction Co., Ltd. are uniquely designed. A tight - fitting sealing strip is used between the cabinet door and the cabinet body, like a protective suit for the file cabinet, effectively blocking external dust particles from entering the cabinet. At the same time, moisture - proof foot pads are equipped at the bottom of the cabinet to isolate ground moisture and keep the internal space dry. Even during the plum - rain season in the south or in an environment with high humidity, your documents and materials can remain dry and tidy, free from mildew erosion.
III. Rational Layout for Efficient Storage
To meet the storage needs of different types of documents in the laboratory, the interior of our file cabinets is designed in a scientific and reasonable way. There are multiple adjustable shelves, allowing you to flexibly adjust the space according to the size and thickness of the materials. Whether it is regular A4 - sized documents, large - scale drawings, or sample albums, they can all find their proper places. In addition, small drawers are thoughtfully designed to store stationery, USB flash drives, and other small items, making it convenient for you to pick them up when referring to materials, greatly improving the efficiency of data retrieval and use.
IV. Safety Protection to Keep Confidentiality
Laboratory documents often involve important confidences such as unpublished scientific research results and sensitive data, so safety issues cannot be ignored. The file cabinets of Guangzhou Cleanroom Construction Co., Ltd. are equipped with an advanced locking system. The high - strength anti - theft lock is combined with a password protection function, and only authorized personnel can open it, effectively preventing the theft or malicious tampering of documents. It comprehensively safeguards your intellectual property rights and experimental data security, leaving you with no worries.
V. Elegant and Compatible with the Environment
In addition to its outstanding functionality, we also pay attention to the appearance design of the file cabinets. The simple and smooth lines, as well as the classic and versatile colors, enable them to easily blend into various laboratory decoration styles. Whether it is a modern and minimalist style or a rigorous industrial style, the file cabinets of Guangzhou Cleanroom Construction Co., Ltd. can complement them perfectly. While enhancing the practicality of the laboratory, they also add a professional aesthetic to the overall environment.
Choosing the laboratory file cabinets of Guangzhou Cleanroom Construction Co., Ltd. means choosing professionalism, quality, and peace of mind. With our profound industry experience and dedication to details, we are committed to creating the most suitable document management solutions for every laboratory. If you are interested in our file cabinets, please feel free to contact us. Guangzhou Cleanroom Construction Co., Ltd. is willing to be your reliable assistant for the efficient operation of the laboratory!
Observation Windows in PCR Laboratories: Illuminating the Path to Precise Experiments
In the PCR laboratory, a fortress for exploring the microscopic world, there is a component that is often overlooked but plays a crucial role—the observation window. As the professional Guangzhou Cleanroom Construction Co., Ltd., we will take you to uncover the mystery of the observation windows in PCR laboratories today.
I. Optical Transparency: Penetrating the Microscopic Mysteries
The observation windows for PCR laboratories meticulously crafted by us are made of special glass with a high light - transmittance rate. This glass undergoes fine optical grinding and coating processes, minimizing the loss of light refraction and reflection. It enables people outside the laboratory to clearly and realistically observe key operational procedures inside the laboratory, such as PCR amplification. Whether it is the sample loading step or the operating status of the equipment, everything can be seen clearly through the observation window. This provides an intuitive perspective for real - time monitoring and quality control of experiments, as if equipping experimenters with a pair of "X - ray eyes" to facilitate precise experimental decision - making.
II. Sealed Protection: Guarding the Pure Land of Experiments
PCR experiments have extremely high requirements for environmental purity. Even a trace of external contamination can lead to deviations in experimental results. The observation windows of Guangzhou Cleanroom Construction Co., Ltd. have achieved the ultimate in sealing performance. High - performance sealing rubber strips are used between the window frame and the wall, combined with a unique embedded installation process, forming an air - tight barrier. This effectively blocks external pollutants such as dust, microorganisms, and aerosols from entering the laboratory. At the same time, it ensures that the internal environment of the laboratory maintains a stable temperature, humidity, and air pressure, allowing precious experimental samples to be tested under the most suitable conditions and safeguarding the accuracy of every experiment.
III. Safety and Stability: Coping with Special Working Conditions
Occasionally, laboratories may face some unexpected situations, such as slight vibrations of instruments and equipment or pressure fluctuations during experiments. Our observation windows fully consider these factors. High - strength aluminum alloy window frames are selected and undergo special reinforcement treatment, featuring excellent seismic and compressive resistance. They can stand firmly during daily use and, even in the event of an accidental impact, can ensure the integrity of the glass, preventing breakage and splashing from causing secondary harm to personnel and experiments, and escorting the safe operation of the laboratory.
IV. Human - centered Design: Meeting Diverse Needs
We are well aware that different PCR laboratories have various layouts and usage habits. Guangzhou Cleanroom Construction Co., Ltd. has incorporated a large number of human - centered considerations into the design of observation windows. The size and shape of the observation windows can be customized according to the actual space of the laboratory. Whether it is the observation demand in a long and narrow corridor - style layout or the planning of a large - area centralized observation area, they can be perfectly adapted. In addition, the edges and corners of the window frame are rounded to avoid accidental collisions and injuries to personnel. These details show our care for users, making the observation window not just a functional component but also an added bonus for the comfortable experience in the laboratory.
Choosing the observation windows for PCR laboratories from Guangzhou Cleanroom Construction Co., Ltd. means choosing professionalism, reliability, and thoughtfulness. With years of industry experience and exquisite craftsmanship, we are committed to creating the highest - quality observation windows for every PCR laboratory, helping researchers continue to explore in the microscopic field. If you are interested in the observation windows for PCR laboratories, please feel free to contact us. Guangzhou Cleanroom Construction Co., Ltd. is willing to be your solid partner on the journey of laboratory construction!
The Ideal Choice for Laboratories: PVC Flooring
In the construction of modern laboratory environments, every detail is crucial to the accuracy and safety of experiments, and the choice of floor materials is of utmost importance. As a professional manufacturer of purification equipment, Guangzhou Cleanroom Construction Co., Ltd. will take you on an in - depth exploration of the outstanding features of laboratory PVC flooring today.
I. Professional Quality, Solid Guarantee
The laboratory PVC flooring produced by our company, Guangzhou Cleanroom Construction Co., Ltd., starts with the strict selection of raw materials, adhering to an attitude of striving for excellence. High - quality PVC resin is used, combined with advanced formulation techniques, endowing it with excellent wear - resistant properties. During the frequent movement of personnel and the handling of equipment in the laboratory, the floor surface is not easily scratched or worn, remaining smooth and new for a long time. This significantly reduces maintenance costs and replacement frequencies, providing a solid guarantee for the continuous and efficient operation of the laboratory.
II. Purification Performance, Protecting the Experimental Environment
Laboratories have extremely high requirements for air cleanliness, and our PVC flooring excels in this regard. Its smooth and dense surface, combined with a seamless splicing design, effectively prevents the hiding and breeding of dust, bacteria, and other tiny particles. This greatly reduces the risk of contamination caused by inadequate floor cleaning. When combined with the overall purification and ventilation system of the laboratory, it can comprehensively contribute to the creation of a high - standard clean experimental space, ensuring that experimental data is not interfered with by external impurities.
III. Safety Protection, Not to Be Ignored
The accidental spillage of chemical reagents is a common situation in laboratories. The PVC flooring of Guangzhou Cleanroom Construction Co., Ltd. has excellent chemical corrosion resistance. Whether it is acidic or alkaline reagents, short - term contact will not cause damage such as erosion, discoloration, or deformation to the floor, safeguarding the integrity and aesthetics of the ground. At the same time, the floor also has good anti - slip properties. Even in a humid environment, it can effectively prevent people from slipping and falling, building a solid safety line for the daily work of experimental personnel.
IV. Custom - made Solutions, Meeting Diverse Needs
Different types of laboratories have various functional layouts and design requirements, which we have fully taken into consideration. Guangzhou Cleanroom Construction Co., Ltd. offers a rich selection of colors and textures, and can customize exclusive PVC flooring solutions according to customer needs. Whether it is the fresh color scheme of a biological laboratory or the steady style of a physical laboratory, we can accurately match it, making the laboratory not only fully functional but also uniquely visually appealing.
Choosing the laboratory PVC flooring of Guangzhou Cleanroom Construction Co., Ltd. means choosing professionalism, quality, and peace of mind. We will continue to use exquisite craftsmanship and innovative concepts to create ideal floor - laying solutions for laboratories around the world, facilitating every scientific exploration and breakthrough. If you want to know more about the product details, please feel free to contact us. Guangzhou Cleanroom Construction Co., Ltd. looks forward to working with you to create a high - quality laboratory environment!
Explore the Laboratory Air Shower
In the field of modern scientific research and experiments, the purity of the laboratory environment is of utmost importance. Every tiny dust particle and microorganism may interfere with the results of precise experiments and even lead to experimental failures. Today, we will take you into the laboratory air shower created by Guangzhou Cleanroom Construction Co., Ltd., and explore the scientific charm and ingenious craftsmanship behind it.
I. The Air Shower - The "Purification Guard" of the Laboratory
The laboratory air shower serves as the first crucial line of defense when entering the laboratory. When personnel or materials are about to enter the core area of the laboratory, they must first pass through the air shower. It uses strong clean airflows to blow the surfaces of the human body and carried items in all directions, forcefully removing dust, hair, dander, and other pollutants attached to them. This effectively prevents foreign dust from entering the laboratory, creating an almost sterile and dust - free environment for the high - precision instruments and sensitive reagents in the laboratory.
II. The Outstanding Design of Cleanroom Construction's Air Shower
1. High - efficiency Filtration System
Guangzhou Cleanroom Construction deeply understands the crucial role of filtration. The air shower is equipped with a multi - layer composite high - efficiency filter. The primary filter can intercept large particles in the air, such as dust and fluff. The medium - efficiency filter further captures slightly smaller dust particles. And the high - efficiency particulate air (HEPA) filter can achieve a filtration efficiency of over 99.97% for particles as small as 0.3 microns or even smaller, ensuring that every wisp of air blown out from the air shower is extremely pure and providing ultimate cleanliness protection for the laboratory.
2. Intelligent Control System
The air shower of Cleanroom Construction is equipped with an advanced intelligent control system, enabling automated operation and precise regulation. After personnel enter the air shower, the induction device starts quickly, automatically closes the air shower door, and then activates the blow - down program. Parameters such as blow - down time and wind speed can be set in advance according to the laboratory's needs. Moreover, the system has a fault self - inspection and alarm function. Once problems such as filter blockage or fan abnormalities occur, it can issue an alarm in a timely manner, notifying maintenance personnel to handle them promptly, ensuring that the air shower is always in the best working condition.
3. Human - oriented Design Details
Considering the user experience, Cleanroom Construction has incorporated many human - oriented elements into the design of the air shower. The spacious and bright interior space ensures that personnel do not feel cramped during the blow - down process. The soft lighting not only ensures visibility but also does not cause visual fatigue. In addition, the air shower is equipped with a voice - prompt function, guiding personnel to correctly complete the blow - down process. Even first - time users can easily get started.
III. Quality Assurance, Stemming from Cleanroom Construction's Professionalism and Perseverance
As a professional manufacturer of purification equipment, Guangzhou Cleanroom Construction Co., Ltd. has an experienced and highly skilled R & D and manufacturing team. From the strict selection of raw materials, to the control of every process in the production process, and then to multiple rounds of inspections before the finished product leaves the factory, Cleanroom Construction always adheres to the highest standards, ensuring that each laboratory air shower is of excellent quality and stable performance. Over the years, with its excellent product quality and high - quality after - sales service, the air showers of Cleanroom Construction have won the trust and praise of many scientific research institutions, university laboratories, and corporate R & D centers, establishing a good reputation in the field of purification equipment.
IV. Join Hands with Cleanroom Construction and Start a Pure Experimental Journey
If you are troubled by creating a clean environment for your laboratory, Guangzhou Cleanroom Construction Co., Ltd. is willing to be your most reliable partner. Our laboratory air shower is not just a piece of equipment; it is a commitment to safeguarding the rigor of scientific experiments. Choosing Cleanroom Construction means choosing professionalism, quality, and peace of mind. Let us work together to promote scientific research progress and create a pure and interference - free experimental space.
Come and contact us now to learn more detailed information about laboratory air showers and other purification equipment, and start a new chapter in laboratory purification!
How to Choose Plant Structural Materials in Purification Workshops?
In the construction of purification workshops, the selection of plant structural materials is as crucial as the cornerstone of building a high - rise building. It is of vital importance yet full of subtleties. Guangzhou Cleanroom Construction Co., Ltd., a professional manufacturer with years of experience in the purification equipment manufacturing industry, is here to clear up the confusion and discuss in detail the key points of choosing plant structural materials for purification workshops.
1. Wall Materials: Emphasizing Both Sturdiness and Cleanliness
The walls are a crucial line of defense for purification workshops to resist external pollution and maintain internal cleanliness. Firstly, color - coated steel plates are the top choice for wall materials in many purification workshops. They possess excellent strength, can withstand certain impacts and pressures, and are not prone to deformation, ensuring the structural stability of the workshop. Moreover, the surface of color - coated steel plates is smooth and flat, which can greatly reduce the chance of dust adhesion and ease the burden of daily cleaning work. At the same time, their good sealing performance prevents the air inside and outside the workshop from leaking into each other, effectively blocking the unfiltered air from the outside. For some purification workshops with special technological requirements, such as the pharmaceutical industry and electronic chip manufacturing, anti - static color - coated steel plates are also used to avoid electrostatic attraction of dust or damage to precision electronic components, comprehensively protecting the clean environment of the workshop.
2. Ceiling Materials: Lightweight and Well - Sealed
The selection of ceiling materials is equally important. The ceiling of a purification workshop needs to balance the two characteristics of lightness and sealing. Lightweight ceiling materials, such as aluminum alloy ceiling panels, have the advantage of being lightweight, which facilitates installation and disassembly, and can save a lot of labor and material resources during later maintenance. More importantly, it has excellent sealing performance, ensuring that there are no gaps at the top of the workshop for dust to sneak in. Some high - end aluminum alloy ceiling panels also come with antibacterial coatings, further inhibiting the growth of microorganisms and creating a pure top - space for the purification workshop. Collaborating with the wall materials, they firmly lock in the clean air.
3. Floor Materials: Prioritizing Wear - Resistance, Anti - Static, and Easy - Cleaning
As an area frequently contacted by personnel and equipment, the floor faces numerous challenges. Epoxy self - leveling floor materials stand out and become the "favorite" for the floors of purification workshops. It has strong wear - resistance, can withstand the long - term friction caused by people walking and equipment moving, and is not prone to problems such as breakage and sanding, maintaining the smoothness of the floor. Static electricity is a major "enemy" in purification workshops. The epoxy self - leveling floor can effectively prevent static electricity, preventing dust from being adsorbed due to static electricity and interfering with the production environment. In addition, its excellent easy - cleaning property makes daily cleaning and disinfection work easy and efficient. Whether it is spilled chemical reagents or fine dust stains, they can be quickly cleaned up, ensuring that the floor is always in the best condition.
4. Door and Window Materials: The Perfect Integration of Air - Tightness and Visibility
Although doors and windows account for a relatively small area in purification workshops, their functions are not to be underestimated. The materials for doors and windows should ensure extremely high air - tightness. Broken - bridge aluminum doors and windows, combined with high - quality rubber seals, can effectively block the penetration of external air, ensuring the air pressure stability inside the workshop and maintaining the air purification effect. At the same time, for operators to observe the situation inside and outside the workshop at any time, double - glazed insulating glass is usually selected as the glass material. It not only enhances the heat - insulation and heat - preservation performance but also ensures good visibility, allowing staff to accurately monitor the dynamics of the workshop without disrupting the clean environment.
5. Structural Support Materials: Stability and Durability Are Paramount
In the construction of the framework of a purification workshop, structural support materials such as steel beams and columns bear the weight of the entire workshop. High - strength steel, such as Q345B section steel, is selected. It has excellent yield strength and tensile strength, firmly supporting the "sky" of the purification workshop. Moreover, steel materials treated with anti - rust measures have a longer service life, avoiding a decrease in structural strength due to rusting and providing a solid guarantee for the long - term stable operation of the purification workshop.
The selection of plant structural materials for purification workshops is a systematic project. Each type of material shoulders important responsibilities, and only by working together can a clean space meeting high standards be created. Guangzhou Cleanroom Construction Co., Ltd., with its professional knowledge and rich experience, can customize the most suitable material solutions for you, helping your purification workshop project get off to a smooth start. If you have any questions or needs regarding the construction of purification workshops, please feel free to contact us at any time!
Construction Standards of Biological Aseptic Rooms
In the era of the booming development of modern life sciences, biopharmaceuticals, and other cutting - edge fields, biological aseptic rooms, as the core places for conducting key experiments and production activities, have attracted much attention regarding their construction standards. Guangzhou Cleanroom Construction Co., Ltd., as a professional manufacturer of purification equipment with years of experience in the industry, will provide you with a detailed interpretation of the construction standards of biological aseptic rooms today.
I. Spatial Layout and Zoning Planning
The layout of a biological aseptic room is by no means random. It needs to be designed scientifically and rigorously according to the experimental or production process. Firstly, distinct functional areas should be demarcated, generally including a preparation area, a buffer area, an experimental operation area, and an auxiliary area. The preparation area is used for the pre - sorting and disinfection of experimental supplies. The buffer area, like a "transition bridge," effectively isolates the outside from the core operation area. Personnel change into clean work clothes and clean their hands here to reduce the risk of bringing in contamination. The experimental operation area is the core of the core, where all delicate operations such as biological sample processing and cell culture are carried out, and it has extremely high requirements for an aseptic environment. The auxiliary area is used to store equipment and reagents, ensuring the convenience of material supply. There should be a reasonable air flow direction among the various areas to avoid cross - contamination. Usually, the principle of a one - way air flow from low - risk areas to high - risk areas is followed.
II. Requirements for the Air Purification System
This is the "life - support system" of a biological aseptic room. The primary - efficiency filter is responsible for intercepting large particles in the air, such as dust and hair, preventing them from entering subsequent purification processes. The medium - efficiency filter further captures particles of 1 - 5μm. The high - efficiency filter, known as the "guardian," should have a filtration efficiency of over 99.99% for microbial aerosol particles of 0.3μm and smaller, ensuring that the air sent into the aseptic room is pure and sterile. At the same time, a stable and reliable air - conditioning system is equipped to precisely regulate the temperature between 22 - 26°C and maintain the relative humidity at 45% - 60%. This creates a suitable and stable temperature and humidity environment for biological experiments or production, inhibits the growth of microorganisms, and ensures the comfort of experimental samples and operators.
III. Selection of Enclosure Structure Materials and Sealing Performance
The materials selected for the walls, ceilings, and floors are directly related to the overall performance of the aseptic room. Color - coated steel plates are preferred for the walls. They have a smooth and flat surface, are not prone to dust accumulation, have good antibacterial properties, and are easy to clean and disinfect. The ceiling also uses color - coated steel plates with good sealing performance to ensure that no dust leaks. For the floor, anti - static, corrosion - resistant, and easy - to - clean epoxy self - leveling floor materials are given priority. They can prevent the adsorption of microorganisms caused by static electricity and can withstand the corrosion of chemical reagents. The entire enclosure structure must ensure extremely high sealing performance. Details such as door seams and corners are sealed with materials such as rubber seals to prevent unpurified air from the outside from sneaking in and disrupting the aseptic environment.
IV. Provision of Disinfection and Sterilization Facilities
A biological aseptic room requires comprehensive disinfection and sterilization methods. Ultraviolet disinfection lamps are common and basic equipment. They are distributed in every corner of the room. When there is no one in the room, they are turned on to damage the DNA structure of microorganisms through ultraviolet irradiation, achieving preliminary disinfection of the air and object surfaces. In addition, appropriate chemical disinfectant spraying devices should be equipped. Depending on different pollution situations, disinfectants such as hydrogen peroxide and alcohol are selected to regularly conduct in - depth disinfection of equipment, countertops, floors, etc. For some heat - resistant experimental utensils, dry - heat sterilizers or autoclaves can be set up to kill microorganisms using high temperatures, ensuring that every corner and every item in the aseptic room is in an aseptic state.
V. Management of Personnel and Material Entry and Exit
Personnel are one of the greatest potential sources of pollution in an aseptic room. Therefore, a strict personnel entry and exit process must be set up. Before entering, personnel need to change into special clean work clothes, hats, masks, and shoe covers in the changing room. After passing through the air shower to blow off the dust attached to their bodies, they can enter the buffer area and then gradually enter the core operation area. The entry and exit of materials should also not be overlooked. Special transfer windows are set up, and methods such as ultraviolet disinfection and self - cleaning functions are used to ensure that the materials are free of surface contamination before entering the aseptic room, preventing the invasion of foreign microorganisms.
The construction standards of biological aseptic rooms cover numerous details, and every link is closely interlocked to create a highly aseptic scientific research and production environment. Guangzhou Cleanroom Construction Co., Ltd., with its exquisite technology and rich experience, can customize high - standard biological aseptic room solutions for customers, helping the life science and biopharmaceutical industries take off. If you have any questions or needs regarding the construction of biological aseptic rooms, please feel free to contact us at any time!
Air - Settling Colony Counts in Cleanrooms In industries with extremely high requirements for the production environment, such
In industries with extremely high requirements for the production environment, such as pharmaceuticals, food, and electronics, Guangzhou Cleanroom Construction Co., Ltd., as a professional manufacturer of purification equipment, is well - aware that every indicator in a cleanroom is crucial for product quality and production safety. Among them, the number of air - settling colonies is one of the key factors for measuring the air quality in a cleanroom. Let's explore this in depth today.
I. What are Air - Settling Colonies?
The air - settling method, in simple terms, utilizes the principle of the natural sedimentation of microorganisms under gravity. Petri dishes containing nutrient agar medium are placed in specific areas of the cleanroom. Microorganisms carried in the air settle onto the surface of the medium. Under suitable temperature and humidity conditions, after a certain period of incubation, the microorganisms will grow and multiply on the medium, forming visible colonies to the naked eye. The number, shape, and size of these colonies provide intuitive evidence for us to assess the degree of microbial contamination in the air of the workshop.
II. Why are They So Important?
For pharmaceutical companies, the production of drugs must be carried out in an aseptic or extremely low - microbial - contaminated environment. A single small colony may contain a large number of pathogenic bacteria or fungi. Once the drug is contaminated, not only will its efficacy be greatly reduced, but it may also lead to serious medical accidents, endangering the health and lives of patients. In food processing workshops, excessive air - settling colonies can cause food to be invaded by microorganisms during the production process, accelerating food spoilage, mildew, shortening the shelf - life, and harming the dietary safety of consumers. In the field of electronics manufacturing, tiny microbial particles adhering to precision electronic components may cause problems such as short - circuits and corrosion, significantly reducing the yield of electronic products. Therefore, strictly controlling the number of air - settling colonies in cleanrooms is the "lifeline" for ensuring the product quality of various industries.
III. Factors Affecting Colony Counts
1. Workshop Ventilation
In a workshop with poor ventilation, the air has poor fluidity, and microorganisms are likely to accumulate, resulting in a naturally high number of settling colonies. A highly efficient and reasonable ventilation system can continuously dilute and remove microorganisms in the air, reducing their concentration in the workshop and the probability of sedimentation. For example, the purification ventilation solutions customized by our company for customers are precisely designed with air volume and air - change rates according to the workshop area, layout, and production process requirements, effectively improving air circulation.
2. Human Activities
Workers are one of the largest sources of microbial contamination in cleanrooms. The human skin, hair, and respiration all release a large number of microorganisms. If personnel enter the workshop without going through strict purification processes, or if they walk around frequently or make large - amplitude movements in the workshop, they will disturb the air and spread microorganisms, increasing the formation of colonies. This requires the workshop to be equipped with a complete set of personnel purification passages, including air showers, changing rooms, etc., and to standardize the operation behaviors of personnel.
3. Material In - and - Out
When raw materials, semi - finished products, packaging materials, and other materials enter and leave the workshop, if they are not effectively disinfected and cleaned, the microorganisms attached to them will "smuggle" into the workshop and become the source of colony growth. The configuration of professional material transfer windows and disinfection equipment can control the entry of materials.
IV. How to Effectively Control Colony Counts
1. Select High - Quality Air Purification Equipment
This is the key to reducing the microbial load from the source. For example, the high - efficiency filters produced by our company have a very high filtration efficiency for microbial aerosol particles as small as 0.3μm or even smaller. Coupled with the primary - efficiency and medium - efficiency filters, they can greatly reduce the number of microorganisms entering the workshop.
2. Optimize Workshop Layout and Cleaning Processes
Reasonably plan the functional areas of the workshop to reduce unnecessary cross - flow of personnel and materials. Develop strict daily cleaning and disinfection systems, and conduct high - frequency and comprehensive cleaning of the floor, walls, equipment surfaces, etc., leaving no "habitat" for microorganisms.
3. Strengthen Personnel Training
Enable every employee entering the workshop to deeply understand the importance of microbial prevention and control, and proficiently master personal hygiene protection and purification operation procedures, reducing the introduction of microorganisms from themselves.
Although the number of air - settling colonies in cleanrooms is just a small indicator, it has a far - reaching impact and is related to the rise and fall of many industries. Guangzhou Cleanroom Construction Co., Ltd., with its professional technology and equipment, is committed to helping enterprises build cleanrooms with low or even no microbial colony contamination, escorting high - quality production. If you have any questions or needs regarding air purification and colony control in cleanrooms, please feel free to contact us at any time!