Guangzhou Cleanroom Construction Co., Ltd. company cases

  In many fields such as life sciences and the pharmaceutical industry, animal experiments are crucial for obtaining reliable data and research results. Constructing animal laboratories in accordance with GLP (Good Laboratory Practice) standards is the foundation for ensuring the accuracy, reliability, and reproducibility of experimental data. Guangzhou Cleanroom Construction Co., Ltd., a company specializing in the production of purification equipment, deeply understands the complexity and importance of animal laboratory engineering construction under GLP standards and will analyze the key construction points in detail for you. 1. Site Selection Considerations According to China's experimental animal management regulations, multiple factors need to be comprehensively weighed when selecting the site for an animal laboratory. It should be far away from noise sources such as factory workshops and busy traffic roads because continuous high - decibel noise can have a negative impact on the physiological and psychological states of experimental animals and interfere with the results of experiments. At the same time, it should be kept away from pollution sources, such as garbage disposal sites and chemical enterprises, to prevent harmful gases, sewage, and other pollutants from contaminating the living environment of experimental animals. From the perspective of wind direction, it needs to be located downwind of the factory area to avoid pollutants from other areas of the factory being blown into the animal laboratory. In addition, setting up a green isolation belt is essential. This can effectively reduce external noise and dust and also play a certain visual isolation role, ensuring that neither the factory area affects the environment of the animal laboratory nor the animal laboratory pollutes the factory area. The experimental animal house should be built in a place with a clean and quiet environment, high and dry terrain, good drainage and ventilation, and guaranteed water and electricity supply. It should also be kept away from factories, bustling residential areas, slaughterhouses, livestock and poultry farms, as well as areas threatened by epidemic sources and public hazards. The animal houses of production and scientific research units should preferably be built independently in a separate area and isolated from other departments. 2. Plane Layout Planning When designing the plane of a GLP animal house, it is necessary to strictly follow the regulations of GB14925 - 2001 Experimental Animal Environment and Facilities and comprehensively consider the flow directions of people, logistics, and waste. A reasonable flow direction plan can effectively avoid cross - contamination and ensure the health of experimental animals and the smooth progress of experiments. Inside the GLP animal house, the number of experimental rooms should be set reasonably according to the scale of experimental animal breeding and the demand for experimental frequency and quantity, on the premise of ensuring that the room area meets the requirements for carrying out a single safety assessment project. For example, IVC cages can be selected for the breeding rooms. The design unit should reasonably plan the outer protection area, building protection area, and breeding protection area, and coordinate the control routes for personnel, animals, materials, and waste. The size of the cleaning preparation room must be determined according to the space occupied by operation contents and facilities such as disinfection and sterilization devices. Moreover, the cleaning preparation room and the cleaning corridor should be separated from the washing room by walls, and there should be no cracks in the walls. 3. Environmental Control Parameters 1. Temperature and Humidity The temperature inside the facility should be precisely maintained between 20°C and 26°C, and the daily temperature difference should not exceed 4°C. This is because experimental animals are sensitive to temperature changes. Too high or too low temperatures and large temperature fluctuations may cause disorders in the physiological functions of animals and affect the accuracy of experimental results. The relative humidity needs to be maintained within the range of 40% - 70%. Appropriate humidity can prevent the respiratory mucosa of animals from drying out, reduce the occurrence of respiratory diseases, and also help maintain the normal physiological functions of the animal's body surface. 2. Air Cleanliness and Air Exchange The environmental cleanliness level of general animal breeding rooms needs to exceed Class 100,000 to meet the requirements of experimental animals. The air exchange rate of the facility is set at 15 - 20 times per hour, and the air flow velocity should not exceed 0.2 meters per second. This can ensure uniform air flow and avoid discomfort to animals caused by direct blowing. Through reasonable air exchange, waste gases such as ammonia and carbon dioxide generated by animals can be timely discharged, and fresh and clean air can be introduced to maintain indoor air quality. 3. Pressure Gradient The air pressure in the clean area is maintained at positive pressure, and the air pressure in the infected area is maintained at negative pressure to prevent air backflow. Positive pressure can prevent external polluted air from entering the clean area and protect experimental animals; negative pressure can ensure that harmful microorganisms in the infected area do not spread to other areas, safeguarding the safety of the laboratory and the surrounding environment. 4. Lighting and Noise In terms of lighting, the artificial lighting inside the facility should be maintained within the range of 150 - 300lx to provide suitable brightness for experimental operations and the life of animals. When there are no animals, the noise inside the facility should be controlled between 40 - 50dB, and when there are animals, the noise should not exceed 60dB to reduce interference to animals and avoid the impact of noise stress on experimental results. 4. Enclosure Structure and Decoration The walls and ceilings of the GLP animal house can be made of color - coated steel plates, special inner arcs, and outer circular columns. This material has good fire - resistance, moisture - resistance, and easy - to - clean properties. The indoor ceiling height is 2.4 meters, which is convenient for equipment installation and daily maintenance. The floor is coated with 2.5 - millimeter - thick epoxy self - leveling paint, which is wear - resistant, corrosion - resistant, and seamless, making it easy to clean and disinfect. The main door is a special purification airtight door equipped with an observation window, which can ensure good airtightness and also facilitate personnel to observe the indoor situation. The inner walls should be smooth, water - resistant, wear - resistant, and resistant to disinfection solution corrosion, and the corners between walls, and between walls and the ceiling or beams should be smooth without sharp edges. Breeding rooms usually do not have external windows, and there are no internal windows between breeding rooms to avoid interference. The doors are preferably made of aluminum alloy airtight doors, and the opening direction must pay attention to the indoor and outdoor pressure differences. For the doors between the barrier and non - barrier areas, devices that prevent opening unless certain conditions are met should be installed. 5. Ventilation and Air - Conditioning System The GLP animal house adopts a central air - conditioning ventilation system, and the air - conditioning equipment is located between the primary and medium - efficiency filters. A set of unitized units provides uninterrupted air supply and power supply services. The units are equipped with two compressors, one in use and one as a backup, ensuring the stable operation of the system. The air supply outlet is located on the side of the compression device, 0.25 meters above the ground. A reasonable location of the air supply outlet can ensure uniform air flow distribution. In addition, the facility should use an independent and stable power supply system to supply power to the SPF - level animal laboratory and be equipped with an emergency power source to deal with sudden power outages and ensure the stable living environment of experimental animals. In order to ensure the safe operation of the facility, a fan failure alarm system is installed in the control room of the central air - conditioning room to facilitate the timely discovery and handling of equipment failures. The air flow organization of the animal house needs to pay special attention to animal comfort and biosafety. The upper - supply and lower - exhaust method is often used, with air supply outlets evenly arranged above the laboratory and air exhaust outlets located below the laboratory. For laboratories where animals are bred in local ventilation cages, the design of upper - supply, lower - side - exhaust, and exhaust air sandwich walls can be adopted. 6. Other System Configurations 1. Water Supply System The animal laboratory uses pipeline water supply. Treated pure water is transported to the laboratories in the barrier system through plastic pipes, and water troughs are set up to supply sterilized drinking water and water for use within the barrier system to experimental animals, ensuring the safety of animal drinking water. 2. Monitoring System Cameras are installed in functional areas such as the entrances and exits, walkways, and laboratory breeding rooms of the laboratory to monitor and observe the laboratory, reducing disturbance to animals. At the same time, it also enables staff to grasp the operation status of the laboratory in real - time and discover abnormalities in a timely manner. The engineering construction of animal laboratories under GLP standards is a systematic and complex project. Every link is closely connected and related to the success or failure of experiments and the welfare of animals. With a professional technical team and rich industry experience, Guangzhou Cleanroom Construction Co., Ltd. can provide you with high - quality purification equipment and overall solutions to help you build an animal laboratory that meets GLP standards.

A Static Pass Box is a transfer device used between cleanrooms or sterile environments. It prevents cross-contamination through physical isolation design while maintaining cleanliness on both sides. Unlike dynamic pass boxes, static pass boxes are not equipped with Fan Filter Units (FFU) and rely on pressure differential principles to control airflow. Working Principle of Static Pass Box Static pass boxes operate through: Dual-door interlock system: Ensures both doors cannot be opened simultaneously Sealed design: Prevents air leakage UV sterilization lamp (optional): For surface disinfection of items Stainless steel or high-quality steel plate material: Easy to clean and disinfect Main Application Fields of Static Pass Box Pharmaceutical industry: For material transfer between areas of different cleanliness levels Electronics manufacturing: Prevents contamination of precision electronic components Food processing: Maintains hygienic production standards Laboratories: Item transfer in biosafety labs Hospitals: Instrument transfer between operating rooms and preparation rooms How to Choose the Right Static Pass Box? Size selection: Determine based on item size Material requirements: 304 or 316 stainless steel preferred Sealing performance: Review air tightness test reports Interlock system: Ensure reliable mechanical or electronic interlock Certification standards: Compliance with GMP, ISO and other certifications Additional features: Consider UV lamp, touch screen control, etc. Installation and Maintenance of Static Pass Box Installation considerations: Must be installed on cleanroom walls Ensure good sealing with the wall Leakage test required after installation Routine maintenance: l Regular cleaning of internal and external surfaces Check door seals for integrity Test interlock function regularly Regular replacement of UV lamps (if equipped) Conclusion Static pass boxes are a cost-effective solution for item transfer in clean environments, particularly suitable for applications with budget constraints but not extreme cleanliness requirements. When purchasing, consider size, material and functional configuration based on actual needs, and ensure suppliers can provide comprehensive after-sales service and technical support.  

Introduction In cleanroom environments, controlling contamination sources is critical to ensuring product quality and production safety. The air shower, serving as the "gatekeeper" of a cleanroom, effectively removes dust and particles from surfaces before personnel or materials enter the sterile area. What Is an Air Shower? An air shower is a high-efficiency purification device typically installed at cleanroom entrances. It uses high-speed clean airflow to blow away contaminants from personnel or materials, reducing the risk of external pollutants entering the controlled environment. It is widely used in industries with stringent cleanliness requirements, such as pharmaceuticals, electronics, food production, and biological laboratories. Core Functions of an Air Shower 1. Removing Surface Contaminants Personnel or materials may carry dust, fibers, or microorganisms before entering a cleanroom. The air shower's high-velocity airflow (typically 20-25 m/s) effectively removes surface particles, minimizing contamination risks. 2. Maintaining Cleanroom Pressure Differentials Air showers usually feature interlocking doors to prevent direct airflow between the cleanroom and external environment, ensuring stable positive pressure and avoiding unfiltered air infiltration. 3. Improving Operational Efficiency Compared to traditional gowning and disinfection processes, air showers provide rapid decontamination, enhancing workflow efficiency while reducing human-induced contamination. 4. Compliance with Industry Standards Many regulations (e.g., GMP, ISO 14644) mandate air showers for high-grade cleanrooms to meet hygiene and safety standards. How Does an Air Shower Work? Sensor Activation: Infrared or pressure sensors trigger the system upon entry. High-Velocity Airflow: HEPA/ULPA filters deliver clean air through nozzles for surface cleaning. Timed Cycle: A 10-30 second blow-off cycle ensures thorough decontamination. Interlock Protection: The inner door only opens after the cycle completes, preventing contamination. Choosing the Right Air Shower Cleanliness Class: Select HEPA (99.99% @ 0.3μm) or ULPA (99.999% @ 0.12μm) filters based on industry needs. Material: Stainless steel or powder-coated steel offers corrosion resistance for humid environments. Automation Level: Smart controls improve usability. Size: Select single-person, double-person, or material-specific models based on traffic volume. Conclusion As the first line of defense against contamination, air showers play a vital role in cleanrooms. Their efficient particle removal and pressure stability make them indispensable in pharmaceuticals, semiconductors, food production, and other high-precision industries. Investing in a high-quality air shower enhances compliance, reduces contamination risks, and safeguards production quality and safety.  

In the field of scientific research, animal laboratories play a crucial and significant role. The air quality within these laboratories is closely related to the health of the experimental animals and the accuracy of the experiments, making purification equipment an essential configuration. However, due to the varying functions and requirements of different types of animal laboratories, the applicable purification equipment also differs. As a professional manufacturer of purification equipment, Guangzhou Cleanroom Construction Co., Ltd. will provide you with a detailed analysis of the purification equipment suitable for different types of animal laboratories.   The Background of the Need for Purification Equipment in Animal Laboratories   In animal laboratories, activities such as the feeding of experimental animals and experimental operations generate various pollutants. These include harmful gases like ammonia and hydrogen sulfide emitted from animal excreta, as well as particulate matters such as animal hair, dander, and microorganisms in the air. These pollutants not only affect the physiological state of the experimental animals and interfere with the experimental results but may also pose a threat to the health of the researchers. Therefore, improving the air quality in the laboratory through purification equipment is the key to ensuring the smooth progress of experiments and the safety of personnel.   Purification Equipment Suitable for Different Types of Animal Laboratories General Animal Laboratories   General animal laboratories have relatively lower requirements for environmental control and are mainly used in scenarios such as teaching demonstrations and preliminary experiments. In these laboratories, the key focuses are on the removal of odors and basic particulate filtration.   Applicable Equipment: Wall-mounted air purification equipment is an excellent choice. Take the wall-mounted purification equipment of Guangzhou Cleanroom Construction Co., Ltd. as an example. It is easy to install and does not occupy much space. It can adsorb odor gases such as ammonia and hydrogen sulfide through a high-efficiency activated carbon filter. At the same time, the equipped primary filter can effectively intercept animal hair, large-particle dust, etc., maintaining the basic cleanliness of the laboratory air and meeting the needs of general experiments.   Animal Laboratories with Barrier Systems   Animal laboratories with barrier systems are mainly used for the breeding of clean-grade and SPF-grade experimental animals. They have extremely high requirements for the airtightness of the environment and the cleanliness of the air. Strict control is needed for the entry and exit of personnel, items, and air to prevent external pollutants from entering.   Applicable Equipment: The modular purification air conditioning unit is the core equipment. This equipment integrates functions such as air filtration, temperature and humidity regulation, and air volume control. In terms of filtration, it adopts a three-stage filtration system consisting of primary, medium, and high-efficiency filters, which can filter out particulate matters as small as 0.3 microns in the air, with a filtration efficiency of over 99.97%, effectively blocking microorganisms and dust. At the same time, it can precisely regulate the indoor temperature and humidity, creating a stable and suitable environment for the experimental animals. The modular purification air conditioning unit of Guangzhou Cleanroom Construction Co., Ltd. is also equipped with an intelligent control system, which can monitor and adjust various parameters in real-time to ensure that the laboratory environment always meets the standards.   Animal Laboratories with Isolation Systems   Animal laboratories with isolation systems are used for the breeding of germ-free animals or for conducting infectious experiments. They have extremely strict requirements for preventing the cross-infection of microorganisms, and the air needs to be highly purified.   Applicable Equipment: Laminar flow purification equipment is the preferred choice. Laminar flow purification equipment can provide unidirectional or bidirectional clean airflows, enabling the air to flow in parallel at a uniform speed and forming an air barrier to prevent the diffusion of pollutants. The laminar flow purification equipment of Guangzhou Cleanroom Construction Co., Ltd. adopts high-efficiency filters and a special airflow design, which can make the interior of the laboratory reach a very high cleanliness level, providing a safe and reliable environment for the breeding of germ-free animals and high-risk experiments. In addition, this equipment is also equipped with an independent ventilation system and a disinfection function, which can thoroughly disinfect the internal environment before and after the experiment, minimizing the risk of infection.   The Professional Support of Guangzhou Cleanroom Construction Co., Ltd.   As an enterprise that has been deeply involved in the field of purification equipment for many years, Guangzhou Cleanroom Construction Co., Ltd. has rich experience in research, development, and production. We not only provide various types of standardized purification equipment as mentioned above but also offer customized solutions according to the specific needs of different laboratories. From the spatial layout of the laboratory, the types of experimental animals, the types of experiments, to the budget planning, our professional team will conduct in-depth analysis and tailor the most suitable purification equipment solutions for our customers. At the same time, we provide comprehensive after-sales services, including equipment installation and debugging, regular maintenance, and technical training, to ensure that our customers have no worries during use.   There is a great deal of knowledge involved in the selection of purification equipment for different types of animal laboratories. Only by choosing the appropriate equipment can we ensure the health of the experimental animals and the accuracy of the experimental results. If you are troubled by the selection of purification equipment for your animal laboratory, you are welcome to contact Guangzhou Cleanroom Construction Co., Ltd. We will use our professional knowledge and high-quality products to safeguard the air quality of your laboratory!

    In animal laboratories, the quality of air is directly related to the accuracy of experiments, the health of animals, and the safety of researchers. With the continuous improvement of scientific research requirements, purification equipment has become a key element in optimizing air quality in animal laboratories. Today, Guangzhou Cleanroom Construction Co., Ltd. will take you on an in-depth exploration of the important role of purification equipment in animal laboratories. Current Situation of Air Quality in Animal Laboratories During the daily operation of animal laboratories, various pollutants that affect air quality are generated. Animal excreta, exhaled gases, and the decomposition of feed and bedding release malodorous gases such as ammonia, hydrogen sulfide, and methyl mercaptan. These gases are not only pungent but also interfere with the physiological functions of experimental animals, affecting the accuracy of experimental data. At the same time, animal hair, dander, and microorganisms such as bacteria, viruses, and fungi float in the air, which can easily cause animal diseases, reduce animal immunity, and further interfere with experimental results. In addition, harmful gases volatilized from some chemical reagents used in animal laboratories also mix into the air, exacerbating air quality problems. Key Roles of Purification Equipment Efficient Removal of Harmful Gases Professional purification equipment is equipped with treatment technologies for different harmful gases. For example, chemical filtration technology is used to utilize specific filter materials to chemically react with harmful gases, converting malodorous gases such as ammonia and hydrogen sulfide into harmless substances, thus effectively reducing the concentration of harmful gases in the air. Some products of Guangzhou Cleanroom Construction Co., Ltd., through carefully selected chemical filter materials, can precisely adsorb and neutralize harmful gas molecules, with an odor removal rate reaching a high level, creating a fresh air environment for the laboratory. Effective Filtration of Microorganisms and Particulates The High-Efficiency Particulate Air (HEPA) filter in purification equipment acts as a “guard” to intercept microorganisms and particulates. HEPA filters can capture particles as small as 0.3 microns in the air, including animal hair, dander, and the vast majority of bacteria, viruses, and other microorganisms, with a filtration efficiency of over 99.97%. This greatly reduces the spread of pathogens in the air, reduces the risk of experimental animals being infected with diseases, safeguards the health of experimental animals, and thus ensures the reliability of experimental results. Regulating Air Circulation, Temperature, and Humidity Good air circulation is crucial for animal laboratories. Purification equipment can promote indoor air circulation through reasonable air duct design and fan configuration, avoiding local air pollution. At the same time, some advanced purification equipment is integrated with temperature and humidity regulation functions. A suitable temperature and humidity environment not only makes experimental animals feel comfortable and reduces physiological changes caused by environmental stress but also inhibits the growth of microorganisms. Generally, the suitable temperature range for experimental animals is 20 - 26°C, and the relative humidity is 30% - 70%. Purification equipment can help maintain such stable environmental conditions. Solutions of Guangzhou Cleanroom Construction Co., Ltd. As a professional manufacturer of purification equipment, Guangzhou Cleanroom Construction Co., Ltd. has developed a series of high-performance purification equipment tailored to the specific needs of animal laboratories. Our suspended purification equipment is easy to install and does not take up floor space. It can purify the air comprehensively from a high position, quickly improving the air quality of the entire laboratory. The vertical internal circulation purification equipment is suitable for laboratories with relatively compact spaces. It efficiently filters indoor air through internal circulation air ducts, effectively removing odors and pollutants. Moreover, all our equipment is carefully designed to operate with extremely low noise, without interfering with experimental operations and animals. In addition, Guangzhou Cleanroom Construction Co., Ltd. also provides personalized customization services. We will tailor the most suitable purification solutions for customers according to the layout, area, types of experimental animals, and air quality requirements of different laboratories, ensuring that every animal laboratory can enjoy high-quality and efficient air purification services. The air quality in animal laboratories is directly related to the success or failure of scientific research work. Purification equipment plays an irreplaceable role in removing harmful gases, filtering microorganisms and particulates, and regulating the air environment. Choosing the products of Guangzhou Cleanroom Construction Co., Ltd. means choosing better air quality assurance for your animal laboratory and laying a solid foundation for the smooth progress of scientific research work. If you have any requirements or questions regarding purification equipment for animal laboratories, please feel free to contact us.