PET Sterile Cold Storage Clean Room Construction Standards
When producing products with extremely high environmental requirements, the PET sterile cold storage clean room plays a crucial role. For Guangzhou Cleanroom Construction Co., Ltd., a manufacturer specializing in purification equipment, it is of great significance to deeply understand its construction standards. Today, let's step into the world of PET sterile cold storage clean room construction.
I. Cleanliness Standards
The cleanliness of the PET sterile cold storage clean room is related to product quality. It is usually classified according to the international standard ISO 14644. Common levels include ISO Class 5 (equivalent to Class 100) and ISO Class 7 (equivalent to Class 10,000). In such a workshop, there are strict restrictions on the number of dust particles in the air. For example, ISO Class 5 requires that the number of particles with a size of 0.5μm or more per cubic meter does not exceed 3,520. This is a basic condition to ensure that the products are sterile and free from contamination.
II. Temperature and Humidity Control Standards
1. Temperature
The temperature of the cold storage workshop is generally controlled between 2 - 8°C to meet the storage needs of some temperature - sensitive products, such as pharmaceuticals and food. Precise temperature control depends on an efficient refrigeration system and accurate temperature monitoring equipment to ensure that the temperature fluctuation in the workshop is within a minimal range.
2. Humidity
The relative humidity is usually maintained at 45% - 65%. Appropriate humidity can prevent products from getting damp and deteriorating, and at the same time avoid the generation of static electricity due to low humidity, which affects production safety and product quality. Advanced humidification and dehumidification equipment are used to achieve precise humidity control.
III. Airflow Organization Standards
1. Unidirectional Flow
In key production areas, the unidirectional flow air - flow organization form is often adopted. Air is sent out from high - efficiency filters and flows at a uniform speed and direction, quickly discharging dust particles and other pollutants from the workshop and effectively reducing the accumulation of pollution.
2. Turbulent Flow
In some auxiliary areas, the turbulent flow form can be adopted. Although the purification effect of turbulent flow is slightly inferior to that of unidirectional flow, it can meet certain cleanliness requirements and the cost is relatively low. By reasonably arranging air supply outlets and air return outlets, the air - flow distribution in the workshop is ensured to be uniform.
IV. Building Material Standards
1. Ground
Materials that are non - slip, corrosion - resistant, and easy to clean, such as epoxy self - leveling floors, should be used. Its seamless feature can effectively prevent the growth of dust and bacteria and has good wear resistance and chemical corrosion resistance.
2. Wall
Color steel plates are generally selected. The surface is smooth and easy to clean and disinfect. At the same time, it has good thermal insulation performance and can maintain the temperature stability in the workshop.
3. Ceiling
The ceiling also adopts color steel plates, which are closely connected to the walls to ensure the airtightness of the entire workshop and prevent external pollutants from entering.
Constructing a PET sterile cold storage clean room is a complex and rigorous process. Each standard is related to production safety and product quality. Guangzhou Cleanroom Construction Co., Ltd., with professional technology and rich experience, is committed to creating clean rooms that meet high standards for customers and helping enterprises produce higher - quality products. If you have relevant construction needs, please feel free to contact us.
Airflow Pressure Difference Control Solutions for Semiconductor Cleanrooms
In the cutting - edge field of semiconductor manufacturing, any slight change in the production environment can have a decisive impact on product quality. As a professional manufacturer with years of in - depth experience in the purification equipment industry, Guangzhou Cleanroom Construction Co., Ltd. deeply understands the core position of airflow pressure difference control in semiconductor cleanrooms. Today, we will comprehensively analyze the airflow pressure difference control solutions for semiconductor cleanrooms, helping you create a stable and efficient production environment.
Airflow Pressure Difference Control: The Key Defense Line in Semiconductor Production
Resisting Pollutant Invasion
The manufacturing process of semiconductor chips is extremely delicate. Once pollutants such as dust particles and microorganisms are mixed in, they may cause serious problems such as short - circuits and open - circuits in chips. Take the lithography process of advanced - process chips as an example. The line width on the chips has reached the nanometer level. A dust particle with a diameter of only 0.1 micrometers is enough to cause deviations in the lithography pattern, resulting in chip scrapping. By reasonably constructing the airflow pressure difference and keeping the cleanroom in a positive - pressure state, external pollutants can be effectively blocked, building an invisible protective barrier for chip production.
Ensuring Stable Process Operation
Semiconductor manufacturing encompasses a variety of complex processes such as lithography, etching, and doping. Each process has different requirements for environmental temperature, humidity, and cleanliness. A stable airflow pressure difference can ensure that the environmental parameters of each area are always maintained within the range required by the process, providing a solid guarantee for the smooth progress of the process. In the etching process, if the airflow is unstable, the distribution of the etching gas will be uneven, leading to inconsistent etching rates and seriously affecting the etching accuracy and product quality of the chips.
Precise Airflow Pressure Difference Control Solutions to Create a Pure Production Space
Scientific Area Division and Precise Pressure Difference Setting
Core Production Area: Key processes such as lithography, etching, and doping are carried out in this area. Here, the requirements for cleanliness and positive pressure are extremely high. It is recommended that the pressure in the core production area is 15 - 25 Pa higher than that in the adjacent auxiliary areas, thus minimizing the risk of external pollutant invasion and ensuring that the chip manufacturing process is not disturbed by pollution.
Auxiliary Production Area: Auxiliary areas such as the material temporary storage area and equipment maintenance area, although the cleanliness requirements are slightly lower than those of the core production area, still need to maintain a certain positive pressure. Generally, it is 5 - 10 Pa higher than areas such as ordinary corridors to prevent pollutants in the corridors from entering the auxiliary area and endangering the environment of the core production area.
Personnel and Material Passages: For the passages where personnel and materials enter and exit the workshop, a reasonable pressure difference gradient needs to be carefully set to form an effective air - lock effect. When entering the clean area from the non - clean area, the pressure gradually increases with each door passed, acting like layers of checkpoints, effectively blocking pollutants from entering the cleanroom along with personnel and materials.
Selecting Advanced Equipment to Achieve Precise Control
High - Precision Pressure Sensors: The high - precision pressure sensors independently developed by Guangzhou Cleanroom Construction Co., Ltd. have excellent performance. Their measurement accuracy can reach ±0.1 Pa, which can accurately capture the pressure changes in each area of the workshop in real - time, ensuring that abnormal pressure fluctuations are detected immediately and providing a strong basis for taking timely countermeasures.
Intelligent Ventilation Control System: This system is closely linked to high - precision pressure sensors. According to the preset pressure difference values, it can automatically and precisely adjust the fan speed and valve opening, achieving intelligent and refined control of the airflow. Once it detects that the pressure in a certain area is lower than the set value, the system will quickly react, automatically increasing the air supply volume or reducing the air exhaust volume to quickly restore the pressure to the normal level.
Comprehensive Maintenance and Management to Continuously Protect the Stability of the Pressure Difference
Regular Calibration and Maintenance to Ensure Equipment Performance
Calibrate the pressure sensors strictly every six months to ensure the accuracy and reliability of the measurement data. At the same time, conduct a comprehensive inspection of the ventilation equipment regularly, carefully check whether the fan impellers are worn, whether the valves can open and close normally, etc., and replace the aging or damaged components in a timely manner to ensure that the equipment is always in the best operating condition.
Conducting Professional Training to Improve Personnel Capabilities
Carry out systematic training on airflow pressure difference control knowledge for the workshop staff, enabling them to deeply understand the significance of pressure difference control and the handling methods of abnormal situations. When a pressure difference alarm occurs, the staff can quickly analyze the possible causes, such as equipment failures and pipeline leaks, and take effective countermeasures in a timely manner to ensure the continuity and stability of workshop production.
In - depth Data Analysis and Continuous Optimization of the Solutions
Build a professional airflow pressure difference data monitoring system and conduct in - depth analysis of the long - term accumulated pressure data. Through data analysis, potential problems can be keenly detected. For example, if the pressure in some areas fluctuates frequently, it may be due to equipment failures or unreasonable air distribution, and then targeted optimization adjustments can be made to continuously improve the airflow pressure difference control solutions.
With profound technical accumulation and rich project experience, Guangzhou Cleanroom Construction Co., Ltd. can not only provide high - quality purification equipment but also customize a full - range of airflow pressure difference control solutions and complete post - maintenance services for your semiconductor cleanroom. If you are planning to build a semiconductor cleanroom or encounter related problems during the operation of an existing workshop, please feel free to contact us. Let's work together to create an industry - leading semiconductor clean production environment and contribute to the development of the semiconductor industry.
Layout Design and Construction Plan for the Seedling Tissue Culture Center
In the current era of rapid development of agricultural modernization and biotechnology, seedling tissue culture technology has become a key means to cultivate high - quality seedlings and improve crop yield and quality. As a professional purification equipment manufacturer, Guangzhou Cleanroom Construction Co., Ltd., with its rich experience and professional technology, presents a comprehensive layout design and construction plan for a seedling tissue culture center.
Design Principles
Scientific Principle: Rigorously based on the technological process and technical requirements of plant tissue culture, rationally plan each functional area to ensure the smooth progress of tissue culture operations. For example, the aseptic operation area is set close to the buffer room to reduce the risk of contamination.
Safety Principle: Pay attention to the safety of personnel and seedlings. Equip complete fire - fighting facilities and emergency evacuation passages. At the same time, carry out special treatment for areas that may produce harmful gases or waste liquids to avoid damage to seedlings.
Energy - saving and Environmental - protection Principle: Select energy - saving equipment and lighting systems, and rationally design the ventilation and air - conditioning systems to reduce energy consumption while ensuring the normal operation of the tissue culture center.
Functional Zoning Planning
Preparation Area: Used for pre - operation preparations such as utensil cleaning and culture medium preparation. Equipped with large - scale cleaning sinks, autoclaves, medicine storage cabinets, and other equipment. The area of this region can be set according to actual needs, generally recommended to account for about 20% of the total area.
Aseptic Operation Area: This is the core area of the tissue culture center, requiring a strictly sterile environment. The main equipment includes aseptic workbenches and ultra - clean workbenches. The air cleanliness is ensured through high - efficiency air filters. The area accounts for about 30% of the total area and needs to maintain a positive - pressure environment to prevent external pollutants from entering.
Culture Area: Place culture racks and incubators for the cultivation and growth of seedlings. The culture area should ensure stable temperature, humidity, and lighting conditions, and an intelligent environmental control system can be installed for precise regulation. This area accounts for the largest proportion, about 40% of the total area.
Acclimatization Area: Before the seedlings are transplanted outdoors, they need to undergo adaptive training in this area. Equipped with special acclimatization equipment and shading facilities, the area accounts for about 10% of the total area.
Equipment Selection
Purification Equipment: The high - efficiency air filters provided by Guangzhou Cleanroom Construction Co., Ltd. can effectively filter tiny particles in the air to ensure that the cleanliness of each area meets the requirements. In the aseptic operation area and the culture area, it is recommended to install our ultra - clean workbenches to provide a sterile operation and growth environment for seedlings.
Environmental Control Equipment: Select an intelligent temperature and humidity control system, which can precisely adjust the temperature and humidity according to the growth needs of different seedlings. At the same time, equipped with a professional lighting system to simulate natural lighting conditions and promote the photosynthesis of seedlings.
Sterilization Equipment: Autoclaves are essential equipment for the sterilization of culture media, utensils, etc. The sterilizers we recommend have the characteristics of high efficiency and safety to ensure the sterilization effect.
Post - construction Maintenance and Management
Regular Equipment Maintenance: Develop an equipment maintenance plan and regularly inspect and maintain purification equipment, environmental control equipment, etc. to ensure the normal operation of the equipment. For example, clean or replace the air filter every quarter.
Personnel Training: Provide professional training for the staff of the tissue culture center to make them familiar with equipment operation and tissue culture processes, and improve work efficiency and quality.
Environmental Monitoring: Regularly monitor the environmental parameters of the tissue culture center, such as temperature, humidity, and cleanliness, and promptly discover and solve problems.
Guangzhou Cleanroom Construction Co., Ltd. not only provides high - quality purification equipment but also offers a full - range of layout design and construction plans and post - construction support services for your seedling tissue culture center. If you are planning to build a seedling tissue culture center, please feel free to contact us at any time. Let's work together to create an efficient and professional tissue culture platform.
Positive and Negative Air Pressures in Cleanrooms
In the construction and operation of cleanrooms, Guangzhou Cleanroom Construction Co., Ltd. deeply understands that the control of positive and negative air pressures is a key factor in ensuring that the production environment meets strict standards. Today, we will introduce you to the relevant knowledge of positive and negative air pressures in cleanrooms in detail.
Basic Concepts of Positive and Negative Pressures
Positive - Pressure Environment
Positive pressure means that the air pressure inside the cleanroom is higher than that of the external environment or adjacent areas. In a positive - pressure state, air flows from the inside of the workshop to the outside. This can effectively prevent pollutants such as dust and microorganisms from the outside from entering the workshop, just like an invisible "air barrier" formed around the workshop. For example, in a precision electronics manufacturing cleanroom, a positive - pressure environment can prevent tiny particles from contaminating electronic products and ensure the yield rate of products.
Negative - Pressure Environment
Negative pressure is the opposite of positive pressure. The air pressure inside the workshop is lower than that of the external or adjacent areas. In this case, air flows from the outside into the workshop, mainly used to prevent harmful pollutants inside the workshop from spreading to other areas. For instance, in biosafety laboratories or some chemical product production workshops, a negative - pressure environment can effectively control pollutants such as harmful gases and aerosols, avoiding harm to the surrounding environment and personnel.
The Important Roles of Positive and Negative Pressures
Ensuring Product Quality
For industries that produce high - precision products, such as semiconductor chip manufacturing, even extremely small dust particles can cause chip short - circuits or performance degradation. A positive - pressure environment can keep out external pollutants and maintain the cleanliness inside the workshop, thus ensuring that product quality is not affected.
Protecting Personnel Safety
In production processes involving biological or chemical hazards, a negative - pressure environment is of great significance. For example, when producing certain potentially infectious drugs in a biopharmaceutical workshop, a negative - pressure environment can prevent harmful microorganisms or chemical substances from leaking outside the workshop, protecting the health and safety of operators and surrounding personnel.
Maintaining Production Stability
A stable positive or negative - pressure environment helps maintain the stability of the air distribution inside the workshop and avoid the spread or cross - contamination of pollutants caused by air flow disorders. This is crucial for the stable operation of continuous production processes, reducing production interruptions or product quality fluctuations caused by environmental factors.
Control Methods of Positive and Negative Pressures
Rational Design of the Ventilation System
The control of positive and negative pressures is achieved by adjusting the volume of air supply and exhaust. When a positive - pressure environment is required, increase the air supply volume so that the amount of air entering the workshop is greater than the amount of air exhausted. Conversely, if a negative - pressure environment is to be formed, increase the exhaust volume so that the amount of air exhausted is more than the amount of air supplied.
Pressure Sensors and Automatic Control Systems
Install high - precision pressure sensors to monitor the air pressure changes inside the workshop in real - time. Once the pressure deviates from the set value, the automatic control system will quickly adjust the operating parameters of the ventilation equipment, such as the rotational speed of the fan, to ensure that the positive and negative pressures are always maintained within the set range.
Optimization of Airflow Organization
Reasonably plan the positions of air supply and exhaust outlets inside the workshop and optimize the airflow organization path. For example, adopt air - supply - from - above and air - exhaust - from - below or side - supply - side - exhaust airflow organization methods to make the air flow evenly distributed inside the workshop, effectively avoiding the occurrence of air - flow dead zones and ensuring the effectiveness of positive and negative pressure control.
Professional Support from Guangzhou Cleanroom Construction Co., Ltd.
As a professional purification equipment manufacturer, Guangzhou Cleanroom Construction Co., Ltd. has rich experience and a professional technical team. During the design, construction, and later maintenance of cleanrooms, we can accurately design and debug the positive and negative air - pressure control systems according to the specific production needs and process characteristics of customers. From the selection of ventilation equipment to the installation and debugging of the entire system, and then to the later maintenance, we provide one - stop services to ensure that each cleanroom can have a stable and reliable positive or negative - pressure environment, providing a solid guarantee for the efficient production and product quality of enterprises.
If you have any questions about the control of positive and negative air pressures in cleanrooms or are preparing to build a cleanroom, please feel free to contact us. Guangzhou Cleanroom Construction Co., Ltd. looks forward to working with you to jointly create a safe, efficient, and clean production environment.
The Selection of Air Conditioning Control Systems for Cleanrooms
In the purification equipment industry, Guangzhou Cleanroom Construction Co., Ltd. has, through years of intensive efforts, deeply realized that the air conditioning control system in cleanrooms is at the core. This system not only directly affects the comfort of the production environment but is also closely linked to product quality, production efficiency, and the operating costs of enterprises. Today, we will provide a detailed analysis of the key points for selecting air conditioning control systems for cleanrooms, along with some real - world cases of well - known enterprises.
Special Requirements of Cleanrooms for Air Conditioning Systems
Cleanrooms are special spaces with strict requirements for environmental cleanliness, temperature and humidity, air distribution, and other parameters. During the production or experimental process, any slight fluctuations in environmental parameters can have serious consequences. For example, in precision electronic component manufacturing workshops, even extremely small dust particles may cause product short - circuits or other quality problems. In biopharmaceutical workshops, unstable temperature and humidity may affect the active ingredients of drugs, thereby affecting the quality and efficacy of drugs. Therefore, the air conditioning control system in cleanrooms must have high - efficiency air - filtering capabilities to ensure that tiny particles in the air can be filtered out; precise temperature and humidity control capabilities to keep the temperature and humidity within extremely strict ranges; and stable and reliable operating performance to ensure the continuity of the production process.
Analysis of Common Air Conditioning Control System Types
Constant Air Volume System (CAV)
The working principle of the constant air volume system is to maintain a constant air supply volume to keep the indoor environment stable. Its advantages lie in its relatively simple structure, relatively low initial investment cost, and relatively easy maintenance. In some small - scale cleanrooms where the production process has a slightly higher tolerance for environmental parameter fluctuations, the constant air volume system can function well. For instance, a small - scale food processing enterprise, [Enterprise Name A], opted for a CAV system in their cleanroom. Since their production process mainly involves packaging and simple processing, with relatively stable environmental requirements, the CAV system met their basic needs at a lower cost. However, when the indoor load changes, the constant air volume system has difficulty flexibly adjusting the air supply volume, which not only easily leads to energy waste but also falls short in precisely controlling temperature and humidity.
Variable Air Volume System (VAV)
The intelligence of the variable air volume system lies in its ability to automatically adjust the air supply volume according to the real - time changes in indoor load, thus achieving precise control of indoor temperature and humidity. This feature enables it to well meet the dynamic environmental requirements of different production processes and can significantly reduce energy consumption. It is especially suitable for large - scale cleanrooms with complex production processes. A well - known automotive parts manufacturing company, [Enterprise Name B], adopted a VAV system in their large - scale cleanroom. Their production lines involve multiple processes with varying heat loads. The VAV system can adjust the air volume in different areas in real - time, ensuring stable temperature and humidity while saving a significant amount of energy. However, the variable air volume system has a relatively high upfront investment cost, and the system debugging and maintenance require professional technicians, which to some extent limits its wide application.
Centralized Purification Air Conditioning System
The centralized purification air conditioning system centrally processes the air and then transports it to each clean area through air ducts. This system is convenient for centralized management and monitoring and can effectively ensure the consistency of air quality throughout the cleanroom. By configuring high - efficiency air - filtering devices, the centralized purification air conditioning system can meet high - level cleanliness requirements and is therefore often used in industries with extremely high cleanliness requirements, such as electronic chip manufacturing and biopharmaceuticals. [Enterprise Name C], a leading semiconductor manufacturer, uses a centralized purification air conditioning system in their cleanrooms. This system can guarantee the ultra - high - level cleanliness required for chip manufacturing, with a large - scale air - handling unit that can handle a large amount of air and ensure the air quality in all production areas is consistent. However, its installation and operation costs are high, and once the system fails, the affected area will be relatively wide, which may seriously affect the entire production process.
Split - type Purification Air Conditioning Units
The split - type purification air conditioning units have the characteristic of flexible installation and can independently control the environmental parameters of each area. For cleanrooms with a relatively scattered layout and small scale, or areas with special process requirements that need to control the environment separately, split - type purification air conditioning units are an ideal choice. A research and development laboratory of a pharmaceutical company, [Enterprise Name D], which has multiple independent experimental areas with different environmental needs, installed split - type purification air conditioning units. Each unit can be adjusted according to the specific requirements of each area, providing a more targeted environmental control solution. However, due to the relative independence of each unit, the coordination and management are more difficult, and the overall energy utilization efficiency is lower than that of the centralized system.
Professional Services of Guangzhou Cleanroom Construction Co., Ltd.
As a professional purification equipment manufacturer, Guangzhou Cleanroom Construction Co., Ltd. not only provides high - quality purification equipment to customers but also has a professional technical team. Our team can, based on the specific conditions of cleanrooms, including the size of the workshop, the special requirements of the production process, the budget constraints of enterprises, and other factors, provide customers with personalized air conditioning control system selection suggestions and comprehensive overall solutions. From system design and planning, to equipment installation and debugging, and then to later maintenance, we provide one - stop services to ensure that each cleanroom is equipped with the most suitable air conditioning control system, providing strong support for the efficient production of enterprises.
If you have any questions about the selection of air conditioning control systems for cleanrooms or are preparing to build a cleanroom, please feel free to contact us. Guangzhou Cleanroom Construction Co., Ltd. looks forward to becoming your reliable partner on the purification journey and jointly creating a clean and efficient production environment.