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Dispensing Booth: Vertical Laminar Flow for Safe Powder Handling

2025-11-24

Latest company case about Dispensing Booth: Vertical Laminar Flow for Safe Powder Handling
Introduction

A Dispensing Booth, also known as a Negative Pressure Weighing Room, is a controlled environment designed for the safe handling of powders and fine particulate materials. By combining vertical laminar airflow with a negative pressure design, the system effectively protects operators, prevents dust escape, and safeguards surrounding areas.

Therefore, dispensing booths are widely used in pharmaceutical manufacturing, biotechnology laboratories, and fine chemical operations, fully meeting GMP compliance requirements.

Airflow Design and Multi-Stage Filtration

The dispensing booth adopts a multi-stage filtration system to ensure stable airflow and high air cleanliness throughout dispensing operations.

Filtration stages include:

  • Primary (Pre-) Filter
    Recirculated air first passes through a primary filter to capture large dust particles and protect downstream filters.

  • Medium-Efficiency Filter
    The pre-filtered air then flows through a medium-efficiency filter, providing secondary filtration and extending HEPA filter service life.

  • HEPA Filter
    Driven by a centrifugal fan, air passes through a high-efficiency HEPA filter to achieve cleanroom-grade air quality.

After filtration, clean air enters the supply plenum. Approximately 90% of the airflow passes through an airflow distribution panel, forming a uniform vertical laminar flow over the working area. The remaining 10% of airflow is discharged through an adjustable exhaust damper.

Both supply and exhaust air streams are HEPA-filtered, ensuring zero dust leakage and preventing secondary contamination.

Dust Control and Negative Pressure Principle

During dispensing operations, dust generated in the working zone is immediately captured by the vertical laminar airflow and directed toward the primary and medium-efficiency filters.

At the same time, the controlled 10% exhaust airflow maintains a stable negative pressure inside the booth. This pressure differential prevents airborne dust from escaping into adjacent rooms, protecting both operators and the surrounding environment.

Through this dual mechanism, the dispensing booth delivers reliable dust containment and enhanced operator safety.

Typical Applications

Dispensing booths are commonly used in:

  • Pharmaceutical powder weighing and dispensing

  • Biotechnology laboratories

  • Fine chemical processing

  • GMP-regulated environments requiring strict contamination control

Any operation involving hazardous or sensitive powders benefits from a negative pressure weighing room.

Conclusion

A Dispensing Booth (Negative Pressure Weighing Room) provides an effective solution for dust control, personnel protection, and GMP compliance. By integrating vertical laminar airflow, negative pressure containment, and multi-stage HEPA filtration, the system creates a clean, safe, and controlled working environment.

As a critical piece of equipment in pharmaceutical and high-standard laboratory settings, a well-designed dispensing booth helps ensure product quality, protect personnel, and maintain regulatory compliance.